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Regina Cassandra is an Indian film actress appearing in Tamil, Telugu and Kannada films. Her recent Tamil film Kedi Billa Killadi Ranga was a big hit. She is best known for her roles in the Telugu films Shiva Manasulo Shruti and Routine Love Story.

Regina started anchoring when she was four for Splash, a kids\' channel and then moved on to work in commercials. Aged 14, she shot for her first film, Kanda Naal Mudhal directed by V. Priya, which also starred Prasanna, Laila and Karthik Kumar. In the film, Regina portrayed Latha, the 21-year-old pregnant sister of Laila\'s character, and has since mentioned that people still find it hard to believe it was her in that role, as she was very young and wore no make-up.

She then appeared alongside fellow newcomer Yogi in Azhagiya Asura, which won good reviews. However the film\'s low-key release meant that the film failed to gain attention, so she took time out from films and then went on to graduate in psychology from Women\'s Christian College, Chennai and Regina took another year off before taking a final call on joining movies.During her break she also acted in short films, most notably Balaji Mohan\'s Kadhalil Sodhappuvadhu Yeppadi alongside Adith Arun, which was later made into a feature film in 2012 under the same name. She also acted in short films Kaanal Neer, Saturday and a few more.

Regina was next seen in the  Suryakaanti by director Chaitanya of Aa Dinagalu fame. The film featured her alongside actor Chetan, and as she could not speak Kannada, she was told to act out scenes in English and add Kannada to it.The film won good reviews and performed moderately at the box office. It was announced that she would feature in the Tamil film Maalai Pozhudhin Mayakathilaey alongside Adith Arun, but the film was eventually delayed and then restarted with a fresh cast.

In 2012, she appeared in Shiva Manasulo Shruti by Tatineni Sathya, which was a remake of the 2009 Tamil film Siva Manasula Sakthi. She was next seen in the Telugu romantic-comedy, Routine Love Story, alongside Sundeep Kishan, which she signed even before her first release in Telugu. Both films were well received by the audience. She finished acting in the Tamil film Kedi Billa Killadi Ranga, as one of the two lead actresses, by Pasanga famous director Pandiaraj. She is working opposite Nara Rohith under the direction of Tatineni Satya in Shankara, and she has also bagged the female lead role opposite Sai Dharam Tej in his upcoming film to be directed AS Ravi Kumar Chowdary. Apart from these two films, Regina is also working on Prakash Raj\'s Tamil-Telugu bilingual Un Samayal Arayil (Vulavacharu Biryani in Telugu), and Kotha Janta directed by Maruthi.